Khairy says the move is mooted in the event the vaccine was found to be unsuitable for use in the country.
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AstraZeneca's contract manufacturer, South Korea's SK Bioscience, will be registered by the Drug Control Authority.
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This follows news reports of side effects of the vaccine in the United Kingdom.
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A 44-year-old man has been admitted to a Melbourne hospital with possible clotting.
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Investigations into reports of rare, and sometimes severe, blood clots continue.
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Its health officials want to see a new analysis of the shot's benefits and risks based on age and gender.
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They say the skirmishes may leave a lasting mark on public trust.
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This is to meet domestic demand as infections surge, sources say.
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AstraZeneca reps in Malaysia met with NPRA last week to explain the situation, says Adham Baba.
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AstraZeneca said the vaccine efficacy rate of 79pct it published on Monday is based on data analysis.
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00The studies lend credence to the vaccine following earlier doubts on the robustness of its data.
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An investigation showed the benefits of AstraZeneca's Covid-19 vaccine outweigh the risks, says the EMA.
0Drug watchdog reviewing reports of bleeding, blood clots and low platelet counts from those who have taken the dose.
0European Medicines Agency and WHO are investigating suspected side effects and will release their findings soon.
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The decision throws the already struggling vaccination campaign in the 27-nation EU into disarray.
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The woman had low number of blood platelets as well as bleeding.
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Prime minister and his cabinet will be the first to receive the Covid-19 vaccine.
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The drugmaker bases its finding on a review covering 17 million people vaccinated in UK and EU.
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