A 43-year-old plane operated by a private airline in mountainous Nepal went missing on Sunday with 22 people on board, and officials said cloudy weather was preventing search helicopters from flying into the area of the flight's last known location.

The Tara Air plane took off from the tourist town of Pokhara, some 125km west of the capital, Kathmandu, for Jomsom, about 80km to the northwest, the officials said.

Flight-tracking website Flightradar24 said the missing De Havilland Canada DHC-6-300 Twin Otter aircraft with...