Veteran opposition MP and lawyer Karpal Singh was killed in an accident near Kampar in Perak this morning.
His long-time personal assistant Michael Cornelius Jayakrishnan, 39, was also killed.
Karpal's son Ram Karpal and the driver were believed to be injured in the accident which occurred at 1.10am near 301.6km northbound marker along the the North-South Highway.
Malaysiakini learnt that Karpal and his son, who is also a lawyer, were heading north for a court case later today.
Photos taken at the scene of the accident - near Gua Tempurung
in Kampar - show the white Toyota Alphard badly damaged.
Contacted later, an Ipoh police spokesperson told Malaysiakini that it is believed the MPV collided with a lorry which switched lanes without indication.
Karpal's other son and Puchong MP Gobind Singh Deo ( left ) told The Star that his father had died on the spot.
"My brother Ram is slightly injured but we are trying to get through to him," he added when the daily contacted him at 3.30am.
According to a police statement later, Ram and driver of the ill-fated car, C Selvam, were not injured. However, Karpal's Indonesian maid suffered severe injuries and she is warded at Ipoh's Hospital Permaisuri Bainun.
The driver of the lorry, which was hit behind by Karpal's car, and its three passengers escaped without injury.
The police said the MPV carrying Karpal and four others hit the slow moving lorry at a hilly stretch of the highway.
The five-tonne lorry was carrying a load of cement, steel and mosaic tiles.
Karpal, 74, was involved in a previous car accident in 2005 where he was paralysed and wheelchair-bound.
The vocal politician graduated from University of Singapore and started his law practice before running for Parliament in 1978.
His long tenure as Jelutong MP and fiery speeches in the Dewan Rakyat earned him the moniker "Tiger of Jelutong".
Karpal had recently relinquished his post as DAP chairperson pending the disposal of his appeal against a sedition charge.
Last month, the High Court found him guilty of uttering seditious words against the Sultan of Perak at the height of the constitutional crisis in 2009.
PM offers condolences
Meanwhile, Prime Minister Najib Abdul Razak conveyed his condolences via Twitter.
"I have just landed at Ankara when I heard the news that YB Karpal Singh died in a road accident. My condolences to the family," read the premier's tweet.
Other netizens also expressed condolences and shock over Karpal's passing.
The bodies of the two deceased, Karpal and Michael, arrived at the Ipoh general hospital at 7.20am.
Penang Chief Minister Lim Guan Eng ( right ) and his deputy Mohd Rashid Hasnon, and former Perak menteri besar Nizar Jamaluddin were there.
They conveyed their condolences to Karpal's sons Gobind and Jagdeep. Karpal's wife was seen crying, while a relative tried to prevent photos from being taken. The bodies were sent for post-mortem.